Genome Changes After Gene Duplication: Haploidy vs. Diploidy
نویسندگان
چکیده
منابع مشابه
The evolution of haploidy and diploidy
Tremendous diversity exists among organisms with respect to their ploidy level, defined as the number of sets of homologous chromosomes per cell. As differences in ploidy represent a potentially major genomic change affecting the evolution of a species, it might be thought that ploidy evolution would be well understood. In fact, our knowledge is fragmentary, and there are several open questions...
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According to the ‘masking hypothesis’, diploids gain an immediate fitness advantage over haploids because diploids, with two copies of every gene, are better able to survive the effects of deleterious recessive mutations. Masking in diploids is, however, a double-edged sword: it allows mutations to persist over time. In contrast, deleterious mutations are revealed in haploid individuals and are...
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Whole genome duplication (WGD) is one of the most important events in the molecular evolution of organisms. In fish species, a WGD is considered to have occurred in the ancestral lineage of teleosts. Recent comprehensive ortholog comparisons among teleost genomes have provided useful data and insights into the fate of redundant genes generated by WGD. Based on these data, a mathematical model i...
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ژورنال
عنوان ژورنال: Genetics
سال: 2010
ISSN: 1943-2631
DOI: 10.1534/genetics.110.118646